
Risk Assessment Tools
Enhance the recognition, evaluation, and management of individuals in healthcare settings who are prone to fractures. This tools aims to empower physicians and other healthcare providers to better identify, assess, and treat patients who may be at risk.
Chinese osteoporosis screening algorithm (COSA)
COSA is an osteoporosis risk prediction tool developed specifically for the Chinese population. Using a patient’s sex, age, weight, and history of non-traumatic fracture, COSA can accurately determine an individual’s risk of osteoporosis as either high or low.
COSA has demonstrated significantly higher accuracy compared to the OSTA in predicting osteoporosis risk among the Hong Kong Chinese population. In real-world external validation, 95% of women aged 65 and older who were flagged as high-risk by COSA were confirmed to have either osteoporosis or osteopenia. This exemplifies COSA’s effectiveness in identifying those at elevated risk enables expedited diagnosis and care interventions where needed most.
Reference: Cheung, Ching-Lung, et al. Osteoporosis and Sarcopenia, vol. 9, no. 1, 2023, pp. 8–13, https://doi.org/10.1016/j.afos.2023.03.009.
Osteoporosis self-assessment tool for Asians (OSTA)
OSTA provides a preliminary assessment of the risk of developing osteoporosis based on the patient’s weight and age.
OSTA was specifically developed to identify high-risk osteoporosis patients among Asian women.
Reference: Koh LK, Sedrine WB, Torralba TP, Kung A, Fujiwara S, Chan SP, Huang QR, Rajatanavin R, Tsai KS, Park HM, Reginster JY; Osteoporos

Fracture Risk Assessment Tool (FRAX)
The purpose of the FRAX® tool is to assess the likelihood of fractures in patients. It utilizes personalized patient models that combine the risks connected to clinical risk factors and bone mineral density (BMD) at the femoral neck.
The FRAX® algorithms give the 10-year probability of fracture. The output is a 10-year probability of hip fracture and the 10-year probability of a major osteoporotic fracture (clinical spine, forearm, hip or shoulder fracture).
Reference: The University of Sheffield. FRAX® Fracture Risk Assessment Tool. Available at: https://www.sheffield.ac.uk/FRAX/tool.aspx?country=20. Accessed 21 October 2019

