New bone gradually replaces old bone.

A robust skeleton requires the contribution of various cell types to support and protect the body. The human body continuously rebuilds new bone to replace old bone. In the case of osteoporosis, the rate of bone breakdown exceeds the rate of bone formation, resulting in weakened bones.

Excessive bone removal leads to bone loss.

Age-related bone loss occurs when the balance between bone removal and replacement is disrupted. Factors such as menopause, aging, and hormone deficiencies can contribute to remodeling and an increased risk of fractures.

Bone loss increases the risk of fractures.

Bone loss weakens the structure of the bones, leading to an elevated risk of fractures, particularly when combined with age-related functional decline and other risk factors.

Step 1: Normal Bone Density

Step 2: Osteopenia

Step 3: Osteoporosis

Step 4: Severe Osteoporosis

Gradual loss of bone density compromises bone strength and resilience, resulting in weakened bones that are highly vulnerable to fractures

Bones are living tissues that undergo continuous remodelling, involving the breakdown of old bone tissue (resorption) and the formation of new bone tissue (formation). This balanced process ensures the strength, structure, and density of our bones. However, in individuals with osteoporosis, this balance is disrupted, leading to excessive bone resorption and inadequate bone formation. As a result, bone density gradually declines, compromising bone strength and increasing the risk of fractures. Minor impacts or falls can easily lead to fractures. After a fracture, the risk of another fracture increases by up to 10 times. Early prevention can help slow the rate of bone loss and reduce the risk of fractures.

International Osteoporosis Foundation. What is Osteoporosis? 2023. Available at: https://www.osteoporosis.foundation/patients/about-osteoporosis.Assessed 15 Jun 2023.